What are the Treatment and Medications of Sickle Cell Disease?

There are several disease are occur in all over the world such as cancer, diabetes, heart diseases and many more diseases. Sickle cell is one of the most common diseases which are spread in all over the world including USA, UK and Australia.

Let us discuss what sickle cell disease is?

Sickle cell disease – It is one of the most common inherited blood disorder in the Unites States which affecting at about 90,000 to 100,000 Americans. This disease is very painful and is linked with many severe health difficulties.

Sickle cell disease is a disease in which attack the red blood cells. It is a genetic disease that indicates when it is passed from the parents. In this disease, the red blood cells look like a sickle that why its name is sickle cell disease. Sickle cell disease is a genetic disease that indicates when it is passed on from your parents.

There are red blood cells in a body which contain a molecule known as haemoglobin that carries oxygen the entire body.  Haemoglobin is smooth round and flexible in a healthy person which allows blood cells to move smoothly through the bloodstream. If you are suffered with the problem of sickle cell disease then the shape of haemoglobin is abnormal which causes red blood cells to become rigid and curved. The odd-shaped cells block flow of blood which is dangerous and can cause anemia, severe pain and other symptoms. Most of the African-Americans are suffered with the problem of sickle cell disease in the United States.

There is a high risk of sickle cell anemia which is also linked with several severe diseases such as severe chest syndrome, damage of bone, stroke and priapism which is painful erection of the penis.

What Causes Sickle Cell Disease? Sickle cell disease is caused by a defective gene known as sickle cell gene. The person is suffered with this disease with two sickle cell gene in which one from father and second one from mother. In this disease, a problem in the haemoglobin-beta gene which is found in chromosome 11 and this defect forms abnormal haemoglobin molecules.

If a child born with one sickle cell gene then it is called as sickle cell trait, he may become a carrier of the disease. These carriers are usually doing not develop symptoms of sickle cell disease.  Generally people are suffered with the sickle cell trait are healthy but they can pass this defect gene to their kids.

Types of sickle cell diseases – There are several types of sickle cell diseases in different forms. The type of sickle cell disease depends upon which types of abnormal haemoglobin you have are as given below –

  • Sickle cell anemia (SS)
  • Sickle Beta-Plus Thalassemia
  • Sickle Hemoglobin- C Disease (SC)
  • Sickle Hemoglobin-D Disease:
  • Sickle Hemoglobin-O Disease

Symptoms of sickle cell disease – There are several sickle cell disease symptoms which are as given below –

  • Bacterial infections
  • Fatigue and anemia
  • Leg ulcers
  • Arthritis
  • Damage of eyes
  • Lung and heart injury
  • There is sudden pooling of blood in the spleen and liver congestion
  • Aseptic necrosis and bone infarcts

It is important to note that sickle cell anemia is typically visible in the first of born. Children and babies may suffer with the problem of abdominal pain, fever, pneumococcal bacterial infections, and painful swellings of the feet and hands.

Treatment of sickle cell disease – The main treatment of sickle cell disease is transplantation of bone marrow is also called as stem cell transplant which provides one possible treat for sickle cell anemia. Generally it is saved for those people whose age is 16 due to increase in risk for those people whose is more than 16 years.  Thus searching a donor for bone marrow is difficult and this method has serious high risks which are linked with it and chances for death.

Generally the sickle cell anemia treatment is expected in relieving symptoms, avoiding disasters, and preventing difficulties. This kids whose age is w2 are suffer with the problem of sickle cell anemia should make regular visits to a doctor for a treatment. The kids whose age is more than 2 and adult people with the problem of sickle cell anemia should attend a doctor at least once throughout the year as per Centers for Disease Control and Prevention. The treatment of this disease is by using medicines for reducing pain and limit complications, blood transfusions as well as a bone marrow transplantation.

Medications of sickle cell anemia – There are several medicines which can be used for the treatment of sickle cell anemia are as given below –

  • Antibiotics – When the kid is of two months with the problem of sickle cell anemia may start using antibiotics penicillin they are at least five years old.  You should prevent infections such as pneumonia that can ne threatening for the life of a baby or child with the problem of sickle cell anemia.
  • Hydroxyurea – It is that type of medicine which is currently used in children and adults with severe pain from the disease of sickle cell anemia. This medicine is also prescribed for those people who are suffering with repeated strokes and frequent transfusions.  This medicine is used in increase the fetal hemoglobin in the blood to resist the sickling of the red blood cells.
  • Pain-relieving medication – The doctor prescribed the pain relieving medicine for reducing pain during the sickle cell disease.